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Modafinil-induced wakefulness can be attenuated by the á1-adrenergic receptor antagonist prazosin; however, modafinil is inactive in other in vitro assay systems known to be responsive to á-adrenergic agonists, such as the rat vas deferens preparation. Modafinil is an oral drug that is prescribed to counteract sleepiness in people especially those that work long hours into the night. The drug is also used to alleviate fatigue and general lethargy. Modafinil stimulates the brain and provides it more energy making people that take it more alert and focused. Use modafinil as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food. If taken with food, modafinil may take longer to work. Shift work sleep problem: take 1 hour before the start of work. Narcolepsy and sleep apnea: take modafinil in the morning. What do i do if i miss a dose? Modafinil is a medication that belongs to the nootropic class of drugs. 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